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Chlamydia Testing

Chlamydia is a bacterial infection most common in young women, though men can also contract this disease. Many people infected with Chlamydia do not manifest any symptoms, but those who do might experience painful urination and uncomfortable sexual intercourse. You might also experience discharge from the penis or vagina, or discharge or spotting from your eyes.
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Condition overview

Chlamydia is an infection with the Chlamydia trachomatis bacteria that is transmitted through sexual contact. It is one of the most common sexually transmitted diseases (STDs) worldwide, with more than 1.7 million cases reported in the US in 2018 (1).

In both women and men, chlamydia can infect the urethra, the tube which passes urine out from the bladder, as well as the rectum.

In women, chlamydia can also infect the cervix, the lower end of the uterus in the vagina. 
Chlamydia in women is a major cause of serious problems such as:
Pelvic inflammatory disease (PID), which is an infection, inflammation, and scarring of the uterus, ovaries, and other female reproductive organs. Approximately 10-15% of women with untreated chlamydia develop PID severe enough to cause symptoms (2)
Inability to get pregnant (infertility) due to damage of the fallopian tubes
Chronic pelvic pain
Ectopic pregnancy, which pregnancy that occurs outside of the uterus
An infected mother can also pass the infection to her baby during childbirth. Chlamydial pneumonia affects 3-16% and chlamydial conjunctivitis (inflammation of the membrane covering the white part of the eye and the inner lining of the eyelid) affects 18-44% of infants born to women who have untreated chlamydial cervicitis at the time of delivery (2).

Chlamydia infection also increases the risk of infection with the human immunodeficiency virus (HIV), the virus that causes AIDS.

Is the condition curable or treatable:

Chlamydia can be cured with antibiotics, which is why it’s important to get tested if you’re at risk. Proper treatment will eliminate the infection but won’t repair any permanent damage that has already been done, and it won’t prevent future infections from occurring.
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Chlamydia Risk Factors

Chlamydia is spread by sexual contact with the vagina, penis, mouth of anus of somebody who is already infected. Anybody who is sexually active can get chlamydia.

Most cases of chlamydia occur in the 15-24 year age group (2). Men who have sex with men are also at higher than average risk to have chlamydia.

Risk factors for chlamydia include:

  • Unprotected sex (without a condom)
  • More than one sexual partner
  • One or more sexual partners with an increased risk of contracting the disease
  • Weakened immune system

Chlamydia can also be spread during childbirth from mother to infant.

Anybody with symptoms of chlamydia (see below) should be tested. Anybody with a sex partner who has an STD should also be tested.

But chlamydia frequently causes no symptoms at all. At least 85% of women with chlamydia affecting the cervix have no symptoms (3). Screening for a disease means getting tested even if no symptoms are present, for the purpose of detecting and treating the disease in the early stages.

Screening for chlamydia is recommended for various groups below.

Screening in nonpregnant women:

  • Sexually active women younger than 25 (screen every year)
  • Older women at high risk for chlamydia due to new or multiple sex partners, or sex partner who has a STD (screen every year)

Screening in pregnant women

  • All pregnant women (first prenatal visit)
  • Pregnant women younger than 25 (screen again in third trimester)
  • Older pregnant women at high risk for chlamydia (screen again in third trimester)

Screening in men

  • Sexually active young men who receive care in settings where the rate of chlamydia is high, such correctional facilities, adolescent clinics, STD clinics
  • Men who have sex with men (screen every year)

Sexually active people with HIV

  • (screen every year)

Chlamydia Symptoms

Most people with chlamydia have no symptoms but can still spread the infection to others through sex.

Symptoms in women include:

  • Bleeding and/or discharge from the cervix
  • Dysuria (burning or pain when urinating)
  • Urinating more frequently than normal
  • Cloudy urine
  • Pain in the pelvis or lower abdomen
  • Painful intercourse

Symptoms in men include:

  • Dysuria
  • Cloudy urine
  • Watery or sticky penile secretions
  • Pain and swelling of the scrotum

Symptoms that can occur in both men and women include:

  • Proctitis (pain, discharge, or bleeding of the rectum)
  • Conjunctivitis

Women at risk for chlamydia or who have been diagnosed with chlamydia should contact their health care provider immediately or go to the emergency room if they have any of these symptoms:

  • Sudden onset of severe pain in the lower abdomen
  • Lower abdominal pain associated with vaginal bleeding or vaginal discharge and a fever of 37.8 C or more
  • Dysuria (burning sensation during urination) or frequent urination and a fever of 37.8 C or more
  • Inability to urinate

Men at risk for chlamydia or who have been diagnosed with chlamydia should contact their health care provider immediately or go to the emergency room if they have any of these symptoms:

  • Discharge from the penis and a fever of 37.8 C or more
  • Dysuria (burning sensation during urination) or frequent urination and a fever of 37.8 C or more
  • Inability to urinate
  • Pain, swelling or tenderness of the scrotum and a fever of 37.8 C or more.

Chlamydia Effects (if left untreated)

If chlamydia is not treated, long term consequences for women include pelvic inflammatory disease and infertility. Pregnant women with chlamydia can also pass the infection on to the infant during childbirth.

Chlamydia Testing

Chlamydia can be diagnosed with a variety of tests. The urine test is the most convenient. The infection can also be detected with a vaginal swab, performed either by the woman herself or by the health care provider. Finally, swabs from the rectal or throat area can also be tested for chlamydia.

Chlamydia Diagnosis prior to treatment

Before starting treatment for chlamydia, your health care provider may ask you about the following:

  • Symptoms
  • Sexual partners
  • Safe sex practices
  • History of STDs in the past
  • Other medical conditions
  • Allergies to medications
  • Possibility of being pregnant. (You may be asked to take a pregnancy test.)

Chlamydia Treatment

Most people with chlamydia have no symptoms but can still spread the infection to others through sex.

Antibiotic treatment of chlamydia is recommended for:

  • Persons who test positive for chlamydia even if they have no symptoms
  • Sexual partners in the last 60 days of those infected with chlamydia even if the infected person or partners have no symptoms
  • Newborns of infected mothers during birth

The purpose of treating is chlamydia is to:

  • Relieve symptoms (if present)
  • Prevent infections causing long term problems
  • Decrease the risk of spreading the infection to others, such as sexual partners or infants (through childbirth)

Chlamydia is treated with antibiotics. The full prescribed course of antibiotics should be taken even if the symptoms improve after a few days. The antibiotic treatment, taken correctly, will cure chlamydia in the vast majority of cases. If antibiotics are not taken properly, the infection might not be eradicated.

For nonpregnant women with urethritis or cervicitis, and men with urethritis, the preferred treatment in most situations is a single 1,000 mg dose of azithromycin. This may require taking two 500 mg tablets. The advantage of this treatment is the convenience of a single dose. An alternative treatment is doxycycline 100 mg twice daily for seven days.

For pregnant women, the recommended treatment is a single 1,000 mg dose of azithromycin. Alternative treatments are amoxicillin or erythromycin for 7 to 14 days, depending on the dose. Doxycycline is not safe for treating chlamydia in pregnant women .

People with HIV can be treated for chlamydia with the same antibiotics that are used for people without HIV.

Treatment of chlamydial infections of the rectum, epididymis (a tube alongside the testicle), mouth/throat, as well as pelvic inflammatory disease, will depend on the extent and severity of the infection.

To prevent spreading chlamydia to others, it is important to avoid sexual activity for 7 days after single-dose antibiotic treatment (e.g. azithromycin) or until a 7-day course of antibiotics is completed (e.g. doxycycline)

Sex partners of someone with chlamydia should be treated for chlamydia. If the partner is not treated at the same time, reinfection can occur.

Retesting is recommended for all infected persons 3 months after treatment to check for reinfection with chlamydia. Additionally, pregnant women as well as people with persistent symptoms and those who were treated with amoxicillin or erythromycin should be tested again at least 3 weeks after treatment.

Some people who are infected with chlamydia also have a gonorrhea infection at the same time. In these cases, treatment includes antibiotics to cure both chlamydia and gonorrhea.

Chlamydia Prevention

The only certain way to avoid getting chlamydia is to not have vaginal, oral, or anal sex.

To prevent chlamydia while you are sexually active, use a latex condom at all times and stay in a mutually monogamous relationship with a partner who does not have chlamydia or other STDs. Mutually monogamous means that you and your partner have sex only with each other and not with other people.

Chlamydia Areas of Uncertainty

It’s unclear whether chlamydia infection in the mouth or throat can cause serious long term health problems.

Important:

Question: Why do I still have symptoms after finishing treatment for chlamydia?

Answer: If you had symptoms when you were diagnosed with chlamydia (not everybody has symptoms) and the symptoms remain or come back again after you’ve finished the antibiotics, there are a few possible explanations. First, you may have become reinfected with a new, separate chlamydia infection. Or you may have another STD, such as gonorrhea.

Reference

  1. Centers for Disease Control and Prevention. Chlamydia. https://www.cdc.gov/std/stats18/chlamydia.htm (Retrieved 06 Jan 2020)
  2. Centers for Disease Control and Prevention. Chlamydia – CDC Fact Sheet (Detailed). https://www.cdc.gov/std/chlamydia/stdfact-chlamydia-detailed.htm (Retrieved 06 Jan 2020)
  3. Hsu K. Clinical manifestations and diagnosis of Chlamydia trachomatis infections. Bloom A, ed. UpToDate. Waltham, MA: UpToDate Inc. https://www.uptodate.com (Retrieved 06Jan2020)
  4. Hsu K. Treatment of Chlamydia trachomatis infection. Bloom A, ed. UpToDate. Waltham, MA: UpToDate Inc. https://www.uptodate.com (Retrieved 06 Jan 2020)
  5. Final Recommendation Statement: Chlamydia and Gonorrhea: Screening. U.S. Preventive Services Task Force. May 2019. https://www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/chlamydia-and-gonorrhea-screening (Retrieved 06 Jan 2020)
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Disclaimer 

Safer STD Testing is an informational referral website. It refers customers to nationally reputed private STD Testing service providers (“Preferred Service Providers” or “Advertisers”). Safer STD Testing is not a medical or healthcare professional facility or a provider of any medical or healthcare services. Safer STD Testing gets compensated on net purchase of products or services by our users referred to such Preferred Service Providers. Click here to read our full disclaimer.
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